Does Minoxidil cause early Facial Aging?

Collagen keeps skin tight, shiny and plump. As we age, collagen production slows and this causes wrinkle formation, dark eye circles and other visible signs of aging. But to say Minoxidil causes this to happen early is controversial and the subject of today’s talk.

The 10 million dollar hair loss medication industry is again going overboard. This time defaming topical minoxidil.
Is the low priced FDA approved medication a source of anguish to those who promote scores of costly products marked at 10 times the cost of Minoxidil? and without both scientific backing and FDA approval!

These are common competitive strategies whereby a controversy is created to pull down a good product to advance another.

There is great bustle online in various forums where hair loss sufferers meet. A buzz that is creating a frenzy that is common when anxious people meet on a common platform.
And they are worried that topical minoxidil causes facial ageing.

Though there is no scientific evidence to this claim, it is creating a big deal of noise. Noise that is
discouraging others from using an established medication for hair loss.

There are only 2 FDA approved medications for hair loss today and both due to some reason or other though found to be beneficial by most doctors have been belittled and often demeaned on social platforms by anonymous trolls.

My phone often rings off the hook with some women terrified when they see facial hair growth showing up after mere 30 days of constant Minoxidil use. But I have never had a call reporting facial ageing. Perhaps with this negative media campaign I will soon start to get these calls as well.

Does anyone possess any substantiated data to share about this whole wave of people that say they experience dilated blood vessels or dark circles around the eyes or fine lines/sunken eyes when using the topical form?
I can well comprehend that applying Minoxidil on eyebrows  could cause tension headaches and dark circles. I can also understand that propylene glycol can cause dermatitis, but, does that cause superficial aging?

But then there is no smoke without fire!
So how did this rumor start?
A growth factor TGF beta (transforming growth factor beta) is responsible for this increased laying down of collagen tissue.
Studies have shown that Minoxidil has the potential to inhibit TGF beta.

Minoxidil does cause a reduction in collagen synthesis and deposition in the scalp.
But then this is a good thing in male pattern baldness.
The basis of androgenetic alopecia is that the body starts to deposit scar tissue around hair follicles which is in medical terms referred to as perifollicular fibrosis.
This happens both in men and women.
In advanced cases this is referred to as scarring alopecia.
This not only speeds up miniaturisation of hair follicles engulfed in this constricting scar but also destroys stem cells.
And secondly, to my mind, people do not wash their hands after applying Minoxidilto their scalp.
They rub their eyes with the same hands. In those with sensitive skin, this causes further enhanced

sensitivity leading to severe around the eyes leading to a vicious cycle. This may be quite rigorous and can damage to small blood vessels under the thin eyelid skin causing extravasation of blood.
Blood collects, blood cells break down, hemoglobin disintegrates into heme that is iron which causes darkish coloration of the eyelids and periocular areas. Constant rubbing of eyes causes inflammation which in turn leads to edema appearing as puffiness of the eyelids- misinterpreted as eyebags, a sign of aging.

So in a nutshell, Minoxidil does affect collagen synthesis but it does so in a wonderful way that is beneficial to our hair. It suppresses the formation of scar tissue that is inimical to the integrity of
follicular stem cells.

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